Chem. Pharm. Bull., 47(2), 295-296, February 1999

Communications to the Editor

Aldovibsanins, Enol Ester Free Vibsane-Type Diterpenes from Viburnum Odoratissimum


Miwa KUBO,a Ih-Sheng CHEN,b Hiroyuki MINAMI,a and Yoshiyasu FUKUYAMA*,a

Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University,a Yamashiro-cho, Tokushima 770-8514, Japan, and School of Pharmacy, Kaohsiung Medical College,b Kaohsiung, Taiwan.
Received December 2, 1998; accepted January 7, 1999

Aldovibsanin A (1), 7-epi-aldovibsanin A (2) and aldovibsanin B (3), novel vibsane-type diterpenes without a b,b-dimethylacrylate group, have been isolated from the leaves of Viburnum odoratissimum, and their structures have been elucidated by spectroscopic analyses and chemical correlation with vibsanin C (4).

Key words Viburnum odoratissimum; Caprifoliaceae; aldovibsanin A; 7-epi-aldovibsanin A; aldovibsanin B; vibsane-type diterpene