Chem. Pharm. Bull., 47(3),454-455, March 1999

Communications to the Editor

An Example of the Co-Occurrence of Enantiomeric Labdane-Type Diterpenes in the Leaves of Mimosa hostilis¹⁾

Yoshiyasu FUKUYAMA,^*,a Ritsuko YOKOYAMA,^a Ayumi OHSAKI,^b Hironobu TAKAHASHI,^a and Hiroyuki MINAMI^a

Faculty of Pharmaceutical Sciences, Tokushima Bunri University,a Yamashiro-cho, Tokushima 770-8514, and Division of Medicinal Chemistry, Institute for Medical and Dental Engineering, Tokyo Medical and Dental University,b Tokyo 101-0062, Japan.
Received December 16, 1998; accepted January 20, 1999

Two labdane-type diterpenes 4 and 5 isolated from the Brazilian medicinal plant Mimosa hostilis were confirmed to have absolute configurations in enantiomeric relation to each other by X-ray crystallographic analysis of p-bromophenyl carbamate derivative 5a and comparison between 4a and 5b, readily available from 5a.

Key words Mimosa hostilis; Leguminosae; 8,15-labdanediol; ent-8(17)-labden-15-ol; labdane-type diterpene; co-occurrence of enantiomers