Chem. Pharm. Bull., 47(9),1338-1340, September 1999

Notes

Secoiridoid Glycosides from Gentiana olivieri

Yoshio TAKEDA,^{* , a} Toshiya MASUDA,^a Gisho HONDA,^b Yoshihisa TAKAISHI,^c Michiho ITO,^b Ozodebek A. ASHURMETOV,^d Olimjon K. KHODZHIMATOV,^d and Hideaki OTSUKA ^e

Faculty of Integrated Arts and Sciences, The University of Tokushima,^a Tokushima 770-8502, Japan, Graduate School of Pharmaceutical Sciences, Kyoto University,^b Sakyo-ku, Kyoto 606-8501, Japan, Faculty of Pharmaceutical Sciences, The University of Tokushima,^c Tokushima 770-8505, Japan, Institute of Botany, Academy of Sciences Uzbekistan Republic,^d 700143, Tashkent, Uzbekistan Republic, and Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine,^e Hiroshima 734-8551, Japan.

From the whole plants of Gentiana olivieri, three new bitter secoiridoid glycosides, olivierosides A (1), B (2) and C (3) were isolated together with the known compounds, gentiopicroside, sweroside, 6'-O- b-D-glucosylgentiopicroside, swertiapunimarin, eustomoside, eustomorusside and septemfidoside, and the structures of the new compounds were elucidated based on spectroscopic and chemical evidence.

Key words Olivieroside; Gentiana olivieri; Gentianaceae; bitter secoiridoid glycoside