Chem. Pharm. Bull., 47(11),1664-1667, November 1999

Notes

Sesquiterpene Alkaloids from Extracts of Tripterygium wilfordii


Hongquan DUAN,a Yoshihisa TAKAISHI,* , a Yongfong JIA,b and Duan LI b

Faculty of Pharmaceutical Sciences, University of Tokushima,a Shomachi 1-78, Tokushima 770-8505, Japan, and School of Pharmacy, Shanghai Medical University,b 138 Yi Xue Yuan Road, Shanghai 200032, China.

Five new sesquiterpene pyridine alkaloids, named wilfordinines D (1), E (2), F (3), G (4) and H (5), along with six known compounds have been isolated from the extracts (TII ) of Tripterygium wilfordii HOOK F. Their structures were elucidated by spectroscopy.

Key words Tripterygium wilfordii ; Celastraceae; sesquiterpene; wilfordinine