Chem. Pharm. Bull.

Chem. Pharm. Bull., 48(5),657-659, May 2000

Regular Articles

Three New Sesquiterpene Lactones from the Pericarps of Illicium merrillianum

Jian-mei HUANG,^a Yoshiyasu FUKUYAMA,^*,a Chun-shu YANG,^b Hiroyuki MINAMI,^a and Masami TANAKA ^a

Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University,^a Yamashiro-cho, Tokushima 770–8514, Japan, and Faculty of Pharmaceutical Sciences, Beijing University of Chinese Medicine,^b Beijing, 100029, China.

Structures of three new sesquiterpene lactones 1—3, isolated from the pericarps of Illicium merrillianum, have been assigned as 14-O-benzoylfloridanolide, 2,10-epoxy-3-dehydroxypseudoanisatin and 7-O-methylpseudo-majucinon the basis of spectroscopic data and chemical transformation. The structure of 2, having an ether linkage between C-2 and C-10, has been confirmed by X-ray crystallographic analysis.

Key words Illicium merrillianum; sesquiterpene lactone; 14-O-benzoylfloridanolide; 2,10-epoxy-3-dehydroxypseudoanisatin; 7-O-methylpseudomajucin

Regular Articles

Three New Sesquiterpene Lactones from the Pericarps of Illicium merrillianum

Jian-mei HUANG,a Yoshiyasu FUKUYAMA,*,a Chun-shu YANG,b Hiroyuki MINAMI,a and Masami TANAKA a

Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University,a Yamashiro-cho, Tokushima 770–8514, Japan, and Faculty of Pharmaceutical Sciences, Beijing University of Chinese Medicine,b Beijing, 100029, China.

Jian-mei HUANG,^a Yoshiyasu FUKUYAMA,^*,a Chun-shu YANG,^b Hiroyuki MINAMI,^a and Masami TANAKA ^a

Institute of Pharmacognosy, Faculty of Pharmaceutical Sciences, Tokushima Bunri University,^a Yamashiro-cho, Tokushima 770–8514, Japan, and Faculty of Pharmaceutical Sciences, Beijing University of Chinese Medicine,^b Beijing, 100029, China.