Chem. Pharm. Bull., 51(1),68-70, January 2003

Regular Articles

Four Guaianolides from Sinodielsia yunnanensis


Nian-He WANG,a Masahiko TANIGUCHI,b Daisuke TSUJI,b Mitsunobu DOI,b Hirohumi OHISHI,b Kenji YOZA,c and Kimiye BABA*,b

a Institute of Botany Jiangsu Province and Academia Sinica; 210014, Nanjing, China: b Osaka University of Pharmaceutical Sciences; 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan: and c Bruker AXS; 3-21-5 Ninomiya, Tsukuba, Ibaraki 305-0051, Japan. * To whom correspondence should be addressed. e-mail: baba@gly.oups.ac.jp

Four new guaianolides, sinodielides A-D (1-4), were isolated from Sinodielsia yunnanensis WOLFF together with a known polyacetylene, falcarindiol, and two known coumarins, bergapten and scopoletin. Their structures were established by spectral and X-ray analyses.

Key words Sinodielsia yunnanensis; Umbelliferae; guaianolide; sinodielide A; sinodielide B; sinodielide C