Chem. Pharm. Bull.

Chem. Pharm. Bull., 51(2),191-193, February 2003

Notes

Two New Flavonoids from Andrographis rothii

Muntha KESAVA REDDY,^a Mopuru VIJAYA BHASKAR REDDY,^a Galla JAYAKRISHNA,^a Duvvuru GUNASEKAR,^*,a Cristelle CAUX,^b and Bernard BODO^b

^a Natural Products Division, Department of Chemistry, Sri Venkateswara University; Tirupati 517 502, India: and ^b Laboratoire de Chimie des Substances Naturelles, ESA 8041 CNRS, Museum National d'Histoire Naturelle; 63 rue Buffon, 75005 Paris, France. * To whom correspondence should be addressed. e-mail: duvvurusekarg@rediffmail.com

Two new flavonoids, 5,7,2′,5′-tetramethoxyflavanone (1) and 5-hydroxy-7,2′-dimethoxyflavone (2), together with two known flavones, skullcapflavone I (3) and echioidin (4) were isolated from the whole plant of Andrographis rothii. The structures of the new compounds were established by extensive one-and two-dimensional (1D- and 2D-) NMR spectral studies.

Key words Andrographis rothii; Acanthaceae; flavonoid

Notes

Two New Flavonoids from Andrographis rothii

Muntha KESAVA REDDY,a Mopuru VIJAYA BHASKAR REDDY,a Galla JAYAKRISHNA,a Duvvuru GUNASEKAR,*,a Cristelle CAUX,b and Bernard BODOb

Muntha KESAVA REDDY,^a Mopuru VIJAYA BHASKAR REDDY,^a Galla JAYAKRISHNA,^a Duvvuru GUNASEKAR,^*,a Cristelle CAUX,^b and Bernard BODO^b