Chem. Pharm. Bull., 53(7),723-739, July 2005

Review

Self-Assembled Complexes of Non-cross-linked Amphiphilic Polymeric Ligands with Inorganic Species: Highly Active and Reusable Solid-Phase Polymeric Catalysts

Yoichi M. A. YAMADA

Institute for Molecular Science; Myodaiji, Okazaki, Aichi 444-8787, Japan. * To whom correspondence should be addressed. e-mail: yyamada@ims.ac.jp

I present herein the development of highly active and reusable polymeric catalysts produced by self-assembly process of non-cross-linked amphiphilic polymeric ligands with inorganic species. Thus, PWAA 1 prepared from H₃PW₁₂O₄₀ and poly[(N-isopropylacrylamide)-co-(acrylamide with ammonium salt)] is suitable for oxidation of alcohols, amines, and sulfides in aqueous hydrogen peroxide. PdAS 2 produced by self-organization of (NH₄)₂PdCl₄ and poly[(N-isopropylacrylamide)₁₀-co-diphenylphosphinostyrene] is an excellent recyclable catalyst for Suzuki-Miyaura reaction in water, water-organic solvent, and organic solvent. It is commercially available from Tokyo Kasei Kogyo (TCI). PdAS-V 3 assembled from (NH₄)₂PdCl₄ and poly[(N-isopropylacrylamide)₅-co-diphenylphosphinostyrene] provides recycling system of itself for Mizorogi-Heck reaction. TiSS 4 made from Ti(O-i-Pr)₄ and poly(styryl-linked binaphtholate-co-styrene) promotes an enantioselective carbonyl-ene reaction as a recyclable catalyst.

Key words immobilized polymeric catalyst; reusable solid-phase catalyst; self-assembly; tungsten; palladium; titanium