Chem. Pharm. Bull., 53(7),847-849, July 2005

Notes

The Isolation and Structure Elucidation of Minor Isoflavonoids from Licorice of Glycyrrhiza glabra Origin

Takeshi KINOSHITA,^*,a Yukiyoshi TAMURA,^b and Kenji MIZUTANI^b

^a Faculty of Pharmaceutical Sciences, Teikyo University; 1091-1 Suarashi, Sagamiko-machi, Tsukui-gun, Kanagawa 199-0195, Japan: and ^b Research Laboratory, Maruzen Pharmaceutical Co., Ltd.; 14703-10 Mukaihigashi-cho, Onomichi 722-0062, Japan. * To whom correspondence should be addressed. e-mail: tk-1948@pharm.teikyo-u.ac.jp

Two new isoflavanone and one new 3-arylcoumarin derivatives, along with a known compound 3,4-didehydroglabridin, were isolated from commercially available licorice of Glycyrrhiza glabra origin, and their structures were elucidated on the basis of both the chemical and spectroscopic evidence.

Key words Glycyrrhiza glabra; licorice; 3-arylcoumarin; isoflavanone; Fabaceae