Chem. Pharm. Bull.

Chem. Pharm. Bull., 53(7),853-855, July 2005

Notes

Chemical Constituents from Roots of Taraxacum formosanum

Yann-Lii LEU,^*^,a Yu-Li WANG,^a Shih-Chin HUANG,^a and Li-Shian SHI^b

^a Graduate Institute of Natural Products, College of Medicine, Chang Gung University; Taoyuan 333, Taiwan: and ^b Department of Biotechnology, National Formosa University; Yunlin 632, Taiwan. * To whom correspondence should be addressed. e-mail: ylleu@mail.cgu.edu.tw

Two new compounds, taraxafolide (1) and (+)-taraxafolin-B (2) together with eighteen known compounds, which include one sesquiterpene, thirteen benzenoids, two indole alkaloids, one pyridine derivative and steroid mixtures were isolated and characterized from the fresh roots of Taraxacum formosanum. Structures of new compounds were determined by spectral analysis. (+)-Taraxafolin-B had the bioactive caffeic acid moiety, but its activity was weaker than α-tocopherol in DPPH radicals scavenging activity assay.

Key words Taraxacum formosanum; Compositae; sesquiterpenoid

Notes

Chemical Constituents from Roots of Taraxacum formosanum

Yann-Lii LEU,*,a Yu-Li WANG,a Shih-Chin HUANG,a and Li-Shian SHIb

a Graduate Institute of Natural Products, College of Medicine, Chang Gung University; Taoyuan 333, Taiwan: and b Department of Biotechnology, National Formosa University; Yunlin 632, Taiwan. * To whom correspondence should be addressed. e-mail: ylleu@mail.cgu.edu.tw

Yann-Lii LEU,^*^,a Yu-Li WANG,^a Shih-Chin HUANG,^a and Li-Shian SHI^b

^a Graduate Institute of Natural Products, College of Medicine, Chang Gung University; Taoyuan 333, Taiwan: and ^b Department of Biotechnology, National Formosa University; Yunlin 632, Taiwan. * To whom correspondence should be addressed. e-mail: ylleu@mail.cgu.edu.tw