Chem. Pharm. Bull., 47(6),809-812, June 1999

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Selective Monodesulfonylation of N,N-Disulfonylarylamines with Tetrabutylammonium Fluoride

Akito YASUHARA,^* Mitsuyoshi KAMEDA, and Takao SAKAMOTO^*

The monodesulfonylation reaction of N,N-bis(methylsulfonyl)-, N,N-bis(phenylsulfonyl)-, and N,N-bis(p-tolylsulfonyl) arylamines easily proceeded using tetrabutylammonium fluoride in tetrahydrofuran under mild conditions to give the corresponding N-monosulfonylarylamines in excellent yields.

Key words tetrabutylammonium fluoride; monodesulfonylation; disulfonylarylamine