Chem. Pharm. Bull., 51(10),1204-1207, October 2003

Notes

Flavone C-Glycosides from Viola yedoensis MAKINO

Chen XIE,^a,b,c Nigel C. VEITCH,^a Peter J. HOUGHTON,^b and Monique S. J. SIMMONDS^*,a

^a Royal Botanic Gardens Kew; Richmond, Surrey, TW9 3DS, U.K.: ^b Department of Pharmacy, King's College London; Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NN, U.K.: and ^c Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences; Xi Bei Wang, Haidian District, Beijing 100094, China. * To whom correspondence should be addressed. e-mail: m.simmonds@kew.org

A new flavone C-glycoside, apigenin 6-C-α-L-arabinopyranosyl-8-C-β-L-arabinopyranoside, has been isolated from Viola yedoensis together with the known compounds, apigenin 6,8-di-C-α-L-arabinopyranoside, apigenin 6-C-α-L-arabinopyranosyl-8-C-β-D-glucopyranoside (isoschaftoside), apigenin 6-C-β-D-glucopyranosyl-8-C-α-L-arabinopyranoside (schaftoside), apigenin 6-C-β-D-glucopyranosyl-8-C-β-L-arabinopyranoside (neoschaftoside), apigenin 6,8-di-C-β-D-glucopyranoside (vicenin-2), apigenin 6-C-α-L-arabinopyranosyl-8-C-β-D-xylopyranoside, apigenin 6-C-β-D-xylopyranosyl-8-C-α-L-arabinopyranoside, luteolin 6-C-β-D-glucopyranoside (isoorientin) and luteolin 6-C-α-L-arabinopyranosyl-8-C-β-D-glucopyranoside (isocarlinoside). The structures were determined by spectroscopic methods and new or revised ¹H- and ¹³C-NMR spectral assignments are proposed for some compounds.

Key words Viola yedoensis; Violaceae; flavone C-glycoside; apigenin; luteolin; NMR