Chem. Pharm. Bull., 51(12),1420-1422, December 2003

Notes

Three Novel 5(6→7)Abeoabietane-Type Diterpenes from the Bark of Taiwania cryptomerioides

Chi-I CHANG,^a Shih-Chang CHIEN,^b Shue-Mei LEE,^c and Yueh-Hsiung KUO^*,b

^a Shu Zen College of Medicine & Management; Kaohsiung, Taiwan, 821 R.O.C.: ^b Department of Chemistry, National Taiwan University; Taipei, Taiwan, 106 R.O.C.: and ^c Department of Nursing, Mackay Junior College of Nursing; Taipei, Taiwan, 112 R.O.C. * To whom correspondence should be addressed. e-mail: yhkuo@ccms.ntu.edu.tw

Three new 5(6→7)abeoabietane diterpenes with the uncommon skeleton of fused 6-5-6 rings were isolated from the bark of Taiwania cryptomerioides designated as taiwaniaquinone F (8), taiwaniaquinol C (9) and taiwaniaquinol D (10). Meanwhile, two known compounds, taiwaniaquinones A (1) and D (4), were also obtained. Their structures were determined principally from spectral evidence.

Key words Taiwania cryptomerioides; Taxodiaceae; diterpene; taiwaniaquinone F; taiwaniaquinol C; taiwaniaquinol D