Chem. Pharm. Bull., 53(8),1037-1039, August 2005

Notes

Cupaniol, a New Branched Polyprenol, from Cupania latifolia

Wataru SAKANE,^a Noriyuki HARA,^a Yoshinori FUJIMOTO,^*,a Yoshihisa TAKAISHI,^b Ricardo ACUÑA,^c Coralia OSORIO,^d and Carmenza DUQUE^d

^a Department of Chemistry and Materials Science, Tokyo Institute of Technology; Meguro-ku, Tokyo 152-8551, Japan: ^b Department of Chemistry, Tokushima University; Sho-machi, Tokushima 770-8505, Japan: ^c Cenicafé, Centro Nacional de Investigaciones del Café; Planalto, Chichiná (Caldas), Colombia: and ^d Departamento de Química, Universidad Nacional de Colombia; AA 14490, Bogotá, Colombia. * To whom correspondence should be addressed. e-mail: fujimoto@cms.titech.ac.jp

A new branched polyprenol, designated cupaniol, has been isolated from the methanol extract of the leaves of Cupania latifolia (Sapindaceae). The structure was determined to be (2E,6E,12E,16E)-3,7,13,17,21-pentamethyl-10-(1-methylethenyl)-2,6,12,16,20-docosapentaen-1-ol on the basis of spectral analysis and conversion to a known compound.

Key words cupaniol; Cupania latifolia; Sapindaceae; branched polyprenol