Chem. Pharm. Bull., 59(4),484-487, April 2011

Note

Pterisolic Acids A-F, New ent-Kaurane Diterpenoids from the Fern Pteris semipinnata

Fei WANG,^*,a,b Ya-Ju LI,^b Fu-Cai REN,^b Guo-Zhu WEI,^b and Ji-Kai LIU^*,a

^a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences; Kunming 650204, China: and ^b BioBioPha Co., Ltd.; Kunming 650204, China. * To whom correspondence should be addressed. e-mail: wangfei@mail.kib.ac.cn, jkliu@mail.kib.ac.cn

Six new ent-15-oxokauran-19-oic acid derivatives, named pterisolic acids A-F (1-6), were isolated from the ethanol extract of the fern Pteris semipinnata (Pteridaceae), and the structures of these new ent-kauranoids were elucidated on the basis of extensive spectroscopic studies and single crystal X-ray diffraction analysis.

Key words Pteris semipinnata; ent-kauranoid; pterisolic acid